A method, an apparatus, and a computer program product are provided for detecting load/store dependency in a memory system by dynamically changing the address width for comparison. An incoming load/store operation must be compared to the operations in the pipeline and the queues to avoid address conflicts. Overall, the present invention introduces a cache hit or cache miss input into the load/store dependency logic. If the incoming load operation is a cache hit, then the quadword boundary address value is used for detection. If the incoming load operation is a cache miss, then the cacheline boundary address value is used for detection. This invention enhances the performance of LHS and LHR operations in a memory system.