The present invention provides a compound of formula (I): ##STR00001## wherein R.sup.1-R.sup.5, R.sup.25, R.sup.26, Y, y, and X.sup.2are as defined herein. The compounds activate human peroxisome proliferater activated receptors (hPPARs) and are useful for the treatment of associated disorders such as dyslipidemia, syndrome X, hypercholesteremia, type II diabetes mellitus, type I diabetes, insulin resistance, hyperlipidemia, and obesity.

 
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> Binding assay employing IGS4, a human G-protein coupled neuromedin receptor

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