The present invention relates to a method and apparatus based on Bloom filters for detecting predefined signatures (a string of bytes) in a network packet payload. A Bloom filter is a data structure for representing a set of strings in order to support membership queries. Hardware Bloom filters isolate all packets that potentially contain predefined signatures. Another independent process eliminates false positives produced by the Bloom filters. The system is implemented on a FPGA platform, resulting in a set of 10,000 strings being scanned in the network data at the line speed of 2.4 Gbps.