A system and method utilize data buffers and data access schedules to improve handling of captured image data of an object under inspection for tomosynthetically processing such captured image data to reconstruct desired cross-sectional images therefrom. One embodiment implements a data buffer communicatively coupled to a radiographic imaging system that allows for storage of captured radiographic image data for at least a portion of multiple different projections of an object under inspection, such as image data associated with one or more angles of view of one or more different regions of the object, and then later that stored data may be used for tomosynthetically reconstructing cross-sectional images for the object under inspection.