There is provided a heteroaryl 5-thio-.beta.-D-glucopyranoside compound of
the following formula, which has an inhibitory effect on SGLT2 activity,
or a pharmaceutically acceptable salt thereof or a hydrate thereof. There
is also provided a pharmaceutical preparation, particularly a
prophylactic or therapeutic agent for diabetes, diabetes-related diseases
or diabetic complications, which comprises such a compound as an active
ingredient. ##STR00001##