An improved therapy is described for patients suffering from pathological conditions characterized by viral, fungal, bacterial, or protozoal load by which such load is reduced. The invention also alleviates symptoms associated with such pathogen-load-characterized conditions by decreasing the pathogen load.The present invention accomplishes those objects by administering substances to patients suffering from pathogen load that enhance the function of the patients' immune systems. The substances are known as "immunoamplifiers," a term that refers to the substances' ability to increase cell-mediated immune system response non-specifically.

 
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> Attenuated rabies virus with nucleoprotein mutation at the phosphorylation site for vaccination against rabies and gene therapy in the CNS

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