A neuromodulation system, comprises an implantable electrode which is implanted within a body adjacent to a target nerve structure to which electric energy is to be applied via the electrode and a connection port which is implanted in the body with a proximal surface thereof substantially flush with an outer surface of a skin of the body, the connection port including a device interface for electrically connecting to an external device which remains external to the body in combination with an electric line extending from the device interface to the electrode for carrying electric energy from the external device to the electrode and a cover selectively closing an opening of the external surface of the implanted connection port.

 
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> 1-[[1-[(2-Amino-6-methyl-4-pyridinyl)methyl]-4-fluoro-4-piperidinyl]carbon- yl]-4-[2-(2-pyridinyl)-3H-imidazo[4,5-b]pyridin-3-yl]piperidine

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