A system for monitoring at least one physiological parameter of a human subject. The system of the present invention features a device with which the human subject regularly interacts, and which is connected to the computational device of the human subject for automatic collection of at least one physiological parameter which is also of medical interest. The device features at least one physiological sensor for collecting the measurement of the physiological parameter. The computational device of the human subject then preferably operates a software program to analyze the data which is collected, in order for the human subject to receive an alert when necessary. Alternatively or additionally, the collected data is sent to a remote computational device which is in communication with the computational device of the human subject for analysis. Optionally, the present invention enables the human subject to receive an alert if a deterioration in the physiological condition of the human subject is detected, thereby enabling the human subject to start preventive medical treatment with trained medical personnel as soon as possible. Thus, the awareness of the human subject about any incipient medical problem is immediately improved, which may result in an increased probability of being able to successfully treat and/or otherwise ameliorate those problems.