A hand-held graphical calculator having a display and an input area is described. The input area includes a maximum of 30 keys and an input device. A hand-held graphical calculator package includes a hand-held graphical calculator for graphically displaying a user-entered expression and a user manual is described. The user manual is a single sheet of instructions describing operation of the graphical calculator.

 
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> Increased and sustained in vivo gene expression using a nucleic acid, histone and amphipathic compound composition

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