The present invention is an educational card game and a method of play thereof, wherein the deck of cards includes at least two cards, each recording information that represents the key concepts from one or more educational topic(s), such that the key concepts comprise part of or all of the contents of the specific topic. Each card must be mutually associated with at least one other card through similar meaning or other logical ties. Through playing the game, players are encouraged to collect associated cards, and they will thus be able to quickly understand the key concepts of a topic, as well as how key concepts are related to each other. The present invention enhances the players' learning experience and serves as an effective educational support tool.