The present invention relates to bicyclic compounds according to formula I, pharmaceutical compositions containing such compounds and methods of using such compounds in the treatment of androgen receptor-associated conditions, such as age-related diseases, for example sarcopenia, ##STR00001## wherein R.sub.1, R.sub.2, R.sub.2' R.sub.5, G, n and W are defined herein.

 
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< Cell-based assay for G-protein-coupled receptor-mediated activity employing a mutated cyclic nucleotide-gated ion channel and a membrane potential dye

> Protein kinase inhibitors comprising ATP mimetics conjugated to peptides or peptidomimetics
~ 00440