Compounds of formula (I), wherein R.sup.1 is a phenyl group which may be optionally substituted; R.sup.2 is selected from hydrogen, C.sub.1-6 alkyl and (CH.sub.2).sub.p--C.sub.3-7cycloalkyl; R.sup.3 is the group: (Formula II), R.sup.4 is selected from hydrogen and C.sub.1-4 alkyl; U is selected from methyl and halogen; X and Y are each selected independently from hydrogen, methyl and halogen; m is selected from 0, 1, 2, 3 and 4, and may be optionally substituted with up to two groups selected independently from C.sub.1-6 alkyl; n is selected from 0, 1 and 2; p is selected from 0, 1 and 2; or pharmaceutically acceptable salts or solvates thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors ##STR00001##

 
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