Compounds of formula (I), wherein R.sup.1 is a phenyl group which may be
optionally substituted; R.sup.2 is selected from hydrogen, C.sub.1-6
alkyl and (CH.sub.2).sub.p--C.sub.3-7cycloalkyl; R.sup.3 is the group:
(Formula II), R.sup.4 is selected from hydrogen and C.sub.1-4 alkyl; U is
selected from methyl and halogen; X and Y are each selected independently
from hydrogen, methyl and halogen; m is selected from 0, 1, 2, 3 and 4,
and may be optionally substituted with up to two groups selected
independently from C.sub.1-6 alkyl; n is selected from 0, 1 and 2; p is
selected from 0, 1 and 2; or pharmaceutically acceptable salts or
solvates thereof, and their use as pharmaceuticals, particularly as p38
kinase inhibitors ##STR00001##