A self-adherent window dressing includes a fabric layer bounded by an edge. The fabric layer has an adhesive side, an opposite non-adhesive side, and an opening therein to allow for viewing therethrough. The opening is defined by a peripheral edge. A transparent film layer closes the opening and has first and second opposing sides. The film layer first side is non-adhesive and is mounted on the fabric layer adhesive side to close the opening in the fabric layer. The film layer second side has a skin adhering adhesive portion and an adhesive-free portion. The adhesive-free portion is disposed partially in the opening and extending beyond the peripheral edge of the opening. The film layer adhesive-free portion is adapted not to stick to a patient's skin, a connector, a catheter, or other medical device disposed between the film layer adhesive-free portion and skin.