According to the invention, there is provided a novel soybean variety designated XB27K06. This invention thus relates to the seeds of soybean variety XB27K06, to the plants of soybean XB27K06 to plant parts of soybean variety XB27K06 and to methods for producing a soybean plant produced by crossing plants of the soybean variety XB27K06 with another soybean plant, using XB27K06 as either the male or the female parent.