An information handling system selectively boots to a normal operation mode having devices and applications configured to operate normally or a multimedia operation mode having devices and applications that support presentation of multimedia information enabled and other devices and applications disabled. In one embodiment, the multimedia mode improves portable information handling system multimedia performance by reducing power consumption to improve battery charge life and by reducing boot time to improve the timeliness of the user experience. For instance, a multimedia module interfaces with the operating system to disable power up of non-multimedia devices, such as networking devices, and non-multimedia applications, such as antivirus applications, while enabling multimedia devices, such as a DVD disc drive, to display multimedia information, such as a DVD movie.