A compound of the formula (I) wherein the variables X.sub.1, X.sub.2, B, D, R.sup.1 to R.sup.7 including R.sup.3', p, y, q, and z, are as defined or a pharmaceutically acceptable salt, solvate, enantiomer, racemate, diastereomer or mixtures thereof, useful for the treatment, prevention or amelioration of obesity and Related Diseases is disclosed ##STR00001##