A biochemical analysis instrument for multiple fluid analyses includes a housing. A sensor for sensing a reaction is disposed in the housing. An aperture is formed in the housing. A test tape housing area is formed in the housing, and the sensor is disposed to selectively move within the housing area; the aperture being formed to provide access to the tape housing area. A cassette is configured to be received within the tape housing area. The cassette includes a case. First and second chambers are formed in the case. A gap is formed in the case. The first chamber and second chamber are disposed at a respective side of the gap. A test tape disposed within the housing extends from the first chamber across the gap to the second chamber. The test tape includes a plurality of active zones disposed at predetermined spaced intervals along the tape for testing an analyte.