A CCFL (cold-cathode fluorescent lamp) driving system for multiple CCFL loads includes a transformer, a CCFL circuit, and a controlling circuit coupled between the transformer and the CCFL circuit. The CCFL circuit includes multiple CCFL loads. The transformer includes a primary winding and a secondary winding, with the primary winding coupled to a voltage source and the secondary winding coupled to the CCFL loads. The controlling circuit includes a part for generating a predetermined voltage signal to power the CCFL loads during a warm-up stage and another part for generating a modulation signal. With such circuit arrangement, each of the multiple CCFL loads is powered from an off state to an operationally-on state.