A focusing mechanism allowing a user to adjust the focus from infinity to a close distance rapidly and precisely, and an optical device utilizing such a focusing mechanism. The focusing unit includes an optical member movable along an optical axis of an optical system, a screw body put into rotation via the rotation of an operation member, a nut body meshing with the screw body and including a cam follower, a cam follower restricting means including a rotation restricting portion for restricting the cam follower from rotating or revolving about a rotation or revolution axis of the operation member, and a rotation restriction releasing portion for releasing the restriction which prevents the rotation or revolution of the cam follower about the rotation or revolution axis of the operation member, and an optical member moving means for moving the optical member along the optical axis via the movement of the nut body along its rotation axis.