Apparatus for introducing a medicament into containers, especially vials,
in which the containers are passed through an enclosure and exposed
therein to a sterilising electron beam. The containers are then conveyed
to a filling station situated outside the enclosure at which a wall part
of the container is punctured with a filling needle and medicament
introduced into the container via the needle then withdrawing the needle.
Preferred apparatus also includes means for heat sealing the puncture
site. A corresponding process is disclosed.