Apparatus and method for addressing and alleviating health problems by applying pulse stimulation via electrode attached to the hand at specific point located along the second metacarpal bone of the hand linking with the index finger. The method includes an apparatus, a system and a scheme to identify the treatment point on the hand, applied in combination, will invoke the human immune system to achieve healing effect or improve symptoms of illness, particularly those caused by inflammation, e.g. asthma, hay fever and related allergies, sore throat and tooth ache.