A method and composition for stimulating the proliferation and
differentiation of stem cells is used to self-repair injury in mammals. A
supplement is administered having an effective dose of substances
selected from blueberry, carnosine, catechin, green tea extract,
VitaBlue, Vitamin D3, Spirulina, AFA or effective combinations and
derivatives of these. For example, a supplement comprising wild
blueberry, green tea extract, carnosine, vitamin D3, and a Spirulina
and/or an AFA-Omega (EtOH) exhibited a synergistic and unexpected
association with substantially increased proliferation of bone marrow
stem cells and CD34+. A therapeutic amount of a substance that is
associated with a substantial increase in stem cells may be used to
prevent and repair damages tissues of the brain, due to stroke, the
heart, due to coronary artery disease or a heart attack.