Compounds of formula (I) ##STR00001## in which R.sub.2, X, Y, Cy, L and Lp(D).sub.n have the meanings given in the specification, are inhibitors of the serine protease, Factor Xa and are useful in the treatment of cardiovascular disorders.

 
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> Stabilization of radiopharmaceutical compositions using hydrophilic 6-hydroxy chromans
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