Disclosed is a method of and apparatus for manufacture of a natural antimicrobial, in which a first mixed solution is created by mixing Taxus extract, Thymus extract and ethanol; a second mixed solution is created by mixing oleic acid with the first mixed solution; a third mixed solution is created by mixing phytoncide with the second mixed solution; and a fourth mixed solution is created by mixing polysorbate with the third mixed solution, and the natural antimicrobial is completed by mixing ethanol, emulsification and water with the fourth mixed solution.