The invention relates to a powder formulation for administration by
inhalation comprising an active substance and a pharmaceutically
acceptable excipient, which composition has the form of a physical
mixture and comprises from 5 to 25 wt. % of the excipient, and wherein
the active substance has a particle size distribution of from 0.5 to 10
.mu.m, and wherein the excipient has a particle size distribution of from
15 to 500 .mu.m.