Imido and amido substituted acylhydroxamidic acids which reduce the levels of TNF.alpha. and inhibit phosphodiesterase in a mammal. A typical embodiment is (3-(1,3-dioxoisoindolin-2-yl)-3-(3-ethoxy-4-methoxyphenyl)propandylamino)- propanoate.

 
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> Amides, preparation and therapeutic use as modulators of CCR-receptor activity
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