An inbred cantaloupe line, designated I446, a hybrid cantaloupe designated I446*I444, and a hybrid cantaloupe designated I446*I407 are disclosed. The invention relates to the seeds of inbred cantaloupe line I446, of hybrid cantaloupe I446*I444, and of hybrid cantaloupe I446*I407, to the plants and plant parts of inbred cantaloupe line I446, of hybrid cantaloupe I446*I444, and of hybrid cantaloupe I446*I407 and to methods for producing a cantaloupe plant, either inbred or hybrid, by crossing the inbred line I446 with itself or another cantaloupe line. The invention further relates to methods for producing a cantaloupe plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other inbred cantaloupe lines derived from the inbred I446.