Methods and apparatus for transporting digital audio-related signals over point-to-point, non-circuit-switched, non-packet-based, local area connections. In one example, multiple digital audio-related signals are combined as a time division multiplexed (TDM) serial bit stream. In addition to the one or more multiplexed digital audio-related signals, the TDM serial bit stream also may be encoded with other information that pertains to one or more of the digital audio-related signals being multiplexed (e.g., data rates of the signals, various data type or status information, timing or other synchronization information, etc.). In one aspect, the TDM serial bit stream is transmitted and received via conventional packet-based network physical layer transceivers (e.g., Ethernet transceivers) that are particularly configured and controlled to transmit and receive essentially continuous bit streams rather than data packets. In another aspect, a "digital audio snake" comprising multiple terminal units that each employs one or more packet-based transceivers is implemented by stringing together two or more such terminal units as a daisy chain connected by a communication medium.