A group of novel phenanthroindolizidine alkaloid compounds as shown and their use in treating cancer. Also disclosed are methods of using phenanthroindolizidine alkoid compounds in suppressing NO and TNF-.alpha. production, inhibiting MEKK1 activity and cyclooxygenase II expression, and treating NO-related disorders.

 
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< Nucleic acids encoding human TNF-.alpha. convertase

> Isolation, identification and characterization of tmst2, a novel member of the TNF-receptor supergene family
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