A sterile connection apparatus is provided for enabling the connection of a
first tube to a transfer tube of a medical solution container. The
apparatus includes a housing having a cover portion which is adapted for
interfitting with a base portion to provide a substantially closed
interior volume. The first tube and the transfer tube of the medical
solution container are introduced within the interior volume and the
housing carries means located therewithin and operable from the outside of
the housing for enabling manipulation of one of the tubes. In this manner,
the first tube may be disconnected from and/or connected to the transfer
tube. Means are provided for sterilizing the tubes within the
substantially closed interior volume.