The subject invention is directed to new and useful neurostimulation
systems that include an implantable pulse generator dimensioned and
configured for implantation in the skull of a patient. The implantable
pulse generator has an electrode operatively associated with a distal end
portion thereof and can be provided with adjustment means, such as an
adjustable biasing member or spring arranged between the electrode to the
distal end portion of the pulse generator. The subject invention is also
directed to systems involving networked neurostimulators that are
configured and adapted to work jointly in accordance with prescribed
treatment protocol to effect a desired recovery from brain injury. Such
networked neurostimulation systems are particularly advantageous for
effecting relatively large and/or relatively distant regions of the
brain. The subject invention is further directed to systems and methods
for motor-evoked potential (MEP)-based neuromodulation. Further, AC
and/or DC stimulation can be utilized, depending on the precise
implementation.