An isolated peptide or polypeptide containing the sequence VSIGLSFPMLP
(SEQ ID NO:1), found in the secreted form of human MUC1, that enhances an
immune response when administered to a mammal, compositions containing
the peptide, host cells producing the peptide and methods of use. The
peptide or polypeptide may be conjugated to a carrier protein and
administered as part of a vaccine or immunogenic composition for
prevention or treatment of a disease or disorder.