The present invention relates to cell-regulatory proteins and to
nucleotide sequences encoding said proteins wherein the proteins have
been found to be potential tumor and/or senescense markers useful for
medical diagnostics and additionally having therapeutical potential as
well as antiapoptotic properties useful for improving cell viability in
cell culture technology. The invention further relates to antibodies
directed against the cell-regulatory proteins and to their use in medical
diagnostics and therapy. The invention further relates to methods for the
manufacture and application of the cell-regulatory proteins and of the
corresponding nucleotide sequences.