The present invention relates to an improved method for mass spectrometric
analysis, in particular for matrix-assisted laser desorption/ionization
time-of-flight mass spectrometry (MALDI-TOF MS) using nanoparticles,
where an analyte is added to a nanoparticle suspension, and the
suspension containing the bound analyte is then deposited directly on a
MALDI sample carrier and investigated by mass spectrometry, and to
nanoparticles suitable for this method.