The present invention provides efficacious preparations for intravenous administration, preparations for external or topical application to skin, preparations for external or topical application to mucosa or cosmetics comprising ginsenosides, in particular, ginsenoside Rb.sub.1 or its derivatives which are useful as skin tissue regeneration/reconstruction promoters or wound healing promoters; and it provides fertilizer additives comprising ginsenosides, in particular, ginsenoside Rb.sub.1 or its derivatives which are useful as plant tissue regeneration/reconstruction promoters. These preparations for intravenous administration, preparations for external or topical application to skin, preparations for external or topical application to mucosa or cosmetics are useful particularly for promoting the tissue regeneration/reconstruction in cases of incised wounds, morsus, bite wounds and/or defect of skin or mucosa or for promoting would healing. The above fertilizer additives are useful particularly for hydroponics and raising of farm products.