Herein disclosed is a novel oncogene named MN or alternatively MN/CA IX. Abnormal expression of the MN gene is shown to signify oncogenesis, and diagnostic/prognostic methods for pre-neoplastic/neoplastic disease to detect or detect and quantitate such abnormal MN gene expression. Also disclosed are methods to treat pre-neoplastic/neoplastic disease involving the MN gene and protein, e.g., methods comprising the use of MN-specific antibodies, anti-idiotype antibodies thereto, and anti-anti-idiotype antibodies, and the use of MN antisense nucleic acids. Further disclosed are methods to identify and block MN binding site(s) and identify MN protein partners(s).

 
Web www.patentalert.com

< Hepatitis C virus non-structural NS3/4A fusion gene

< Methods and compositions for administration of iron for the treatment of restless leg syndrome

> Composition comprising camptothecin or a comptothecin derivative and a platin derivative for the treatment of cancer

> Tumor specific monoclonal antibodies

~ 00291