Computer-based methods and systems for automatically determining convergence when registering image sets are provided. Example embodiments provide an Enhanced Image Registration System (EIRS), which includes an Image Comparison Module, a Transformation Optimizer, and a Convergence Calculator. When the EIRS receives two image sets to align, the Image Comparison Module compares two image sets to determine or measure how closely the image sets are aligned. The Transformation Optimizer determines an appropriate transformation to apply to one of the image sets to align it with the reference image set. The Transformation Optimizer then applies the determined transformation. The Convergence Calculator examines one or more points within the transformed image set to determine when convergence is attained.