Melanin-concentrating hormone (MCH) receptor antagonists are disclosed having utility for the treatment of MCH receptor-based disorders such as obesity. The compounds of this invention have the following structure: including stereoisomers, prodrugs, and pharmaceutically acceptable salts thereof, wherein m, n, X, R.sub.1, R.sub.2, R.sub.3, R.sub.4, and R.sub.5 are as defined herein. Also disclosed are compositions containing a compound of this invention, as well as methods relating to the use thereof.

 
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