Novel sulphones of formula I are disclosed: ##STR00001## The compounds modulate the processing of amyloid precursor protein by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease.

 
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< Salicylamide-lanthanide complexes for use as luminescent markers

< Dark quenchers for donor-acceptor energy transfer

> Method for evaluating inhibition of aspartic proteases

> Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein

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