Compositions and methods for administering a therapeutic agent to a mammal
are disclosed. The compositions comprise either (i) vesicles comprising
an amphiphilic substituted fullerene, wherein the therapeutic agent is
present in the vesicle interior or between layers of the vesicle wall,
(ii) a substituted fullerene, comprising a fullerene core and a
functional moiety, wherein the therapeutic agent is associated with the
substituted fullerene, or (iii) carbon nanotubes, wherein the therapeutic
agent is covalently bonded to the carbon nanotubes.