The pick-up device provides an elongated hollow cylindrical body including a handle at one end and a bail arrangement at the other end. The handle includes a trigger mechanism extending through the hollow body and terminating in a crank coupling the pair of bails in the bail assembly, so that one bail is fixed and the other bail is movable with respect to the fixed bail. The body includes a roller upon which a supply of litter bags is placed, and the body includes an elongated slot with finger openings so that a single bag from the supply can be withdrawn from the roll, separated from the roll, and installed on the pair of bails in the bail arrangement. A cable is employed for releasably actuating the bail and mechanism is provided for rotatably mounting the handle and trigger mechanism onto one end of the body so that the handle can be rotated as to expose the aft end of the body permitting a new roll of bags to be installed. Alternately, a bag supply cartridge may be installed through the side of the body.