The present invention relates to a compound formula [I]: wherein ect., X is bond, --CH.sub.2--, etc., Y is bond, --O--(CH.sub.2).sub.n-- (in which n is 1, 2, 3 or 4), etc., Z is cyano, tetrazolyl, etc., R.sup.1 is hydrogen, lower alkyl, etc., R.sup.2 is hydrogen or an amino protective group, R.sup.3 is hydrogen or lower alkyl, R.sup.4 is hydrogen or lower alkyl, R.sup.5 and R.sup.8 are each independently hydrogen, halogen, hydroxy, lower alkyl, etc., R.sup.6 is hydrogen, lower alkyl, etc., R.sup.9 is hydrogen or lower alkyl, and i is 1 or 2, or a salt thereof. The compound [I] of the present invention and pharmaceutically acceptable salts thereof are useful for the prophylactic and/or the therapeutic treatment of pollakiurea or urinary incontinence.

 
Web www.patentalert.com

< Orthomolecular medical use of L-citrulline for capillary endothelial protection and adjacent cell protection in neurodegenerative disease

< Cytokine inhibitors

> Inhibitors against the activation of ap-1 and nfat

> Indole compounds useful as serotonin selective agents

~ 00261