A gradient material comprising at least two types of nanofibers distributed non-uniformly throughout the material to form one or more gradients is provided. In one embodiment, the at least two types of nanofibers intertwine to form a single layer of material, i.e., are at least partially physically intertwined, i.e., entangled with one another in a multi-component material. Such intertwining can occur when both types of nanofibers are deposited substantially simultaneously in an overlapping region. In another embodiment, the at least two types of nanofibers combine to form a plurality of layers. The nanofibers can be electrospun fibers. The material can have a gradient in the planar and/or thickness directions. Embodiments of the invention also provide processes for producing the gradient nanofiber material. The materials are useful for any type of disposable garment, wipe, hospital garment, face mask, sterile wrap, air filter, water filter and so forth. Materials described herein can provide strong and varying surface effects, such as wicking. In one embodiment, hydrophobic fibers have a sufficiently small diameter to create a lotus effect.