A system, method and computer program product are disclosed for transmitting a datagram in a wireless multiplexing framework. A datagram destined to a destination in a network is received and a wireless connection is then selected from a set of wireless connections. The received datagram is then processed to associate an intermediary destination with the datagram. The datagram is subsequently transmitted to the associated intermediary destination via the selected wireless connection. From the associated intermediary destination, the datagram is then forwarded to the destination utilizing the network.