A prevention or intervention program for Metabolic Syndrome interposes a trusted mediator group between a seller of a biomedical product or service and provider-patient interactions in a healthcare setting, wherein the seller directly or indirectly engages the services of the trusted mediator group, and ordinarily for consideration. The trusted mediator group provides web-based resources on which there is an internet-implemented mechanism to motivate participation by both healthcare providers and patients pre-qualified on the basis of specified criteria as well as motivate changes in participant behavior regarding desirable disease prevention or intervention practices, thereby encouraging sales of the seller's biomedical product or service. Participants are motivated by that utilize indirect predictive motivators, as correlated to a patient's particular cognitive style type, exceptional credibility of biomedical information presented, or computed risk of developing future disease.