A composite wick structure of a heat pipe includes wick structure fabricated from a woven mesh and sintered powder. The woven mesh is attached to an internal sidewall of a tubular member, while the sintered powder is coated on at least one side of the internal sidewall. By the better capillary force provided by the sintered powder, the liquid-phase working fluid can reflow to the bottom of the heat pipe quickly to enhance the heat transmission efficiency. Further, the problems of poor capillary effect of the woven mesh and the problems caused by usage of an axial rod during the process of applying sintered powder can be resolved.