The present invention provides an isolated nucleic acid encoding an endoplasmic reticulum associated amyloid-beta peptide binding (ERAB) polypeptide. The ERAB polypeptide may comprise human ERAB polypeptide. The present invention provides a purified ERAB polypeptide, as well as a method for treating a neurodegenerative condition in a subject which comprises administering to the subject an agent in amount effective to inhibit ERAB polypeptide binding to amyloid-beta peptide so as to thereby treat the neurodegenerative condition.

 
Web www.patentalert.com

< Use of neuronal apoptosis inhibitor protein (NAIP)

< Diagnostic sequencing by a combination of specific cleavage and mass spectrometry

> Expression and purification of ATM protein using vaccinia virus

> Method of identifying inhibitors of C—C chemokine receptor 3

~ 00237