A sand control screen assembly (60) comprises a base pipe (62) having at least one opening (64) that allows fluid flow therethrough and a filter medium (66) positioned about the exterior of the base pipe (62) that allows fluid flow therethrough and prevents particulate flow therethrough. An inflatable seal member (72) is disposed within the at least one opening (64) of the base pipe (62) and controls fluid flow through the at least one opening (64). An inflation fluid source (74) is in fluid communication with the inflatable seal member (72) and provides an inflation fluid to the inflatable seal member (72) to selectively urge the inflatable seal member (72) into sealing engagement with the at least one opening (64).