Aryl-substituted piperazine derivatives are provided. Such compounds may be used to modulate MCH receptor activity in vivo or in vitro, and are particularly useful in the treatment of a variety of metabolic, feeding and sexual disorders in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for treating such disorders are provided, as are methods for using such ligands for detecting MCH receptors (e.g., receptor localization studies).

 
Web www.patentalert.com

< Protein kinase modulators and method of use

< Six-membered heterocycles useful as serine protease inhibitors

> Prophylactic or therapeutic agents for diseases associated with dysfunction of NOS

> Pyridazine derivatives and their use as therapeutic agents

~ 00232