A body frame damping structure in a saddle-type vehicle includes a front fork steerably supported at a front end portion of a body frame and a front wheel supported at lower end portions of the front fork. The body frame damping structure also includes a rear arm pivotally supported at a rear portion of the body frame by a pivot support shaft so as to be swingable up and down and a rear wheel supported at a swinging end of the rear arm. Dampers are disposed so as to bridge a first portion of the body frame with a second portion of the body frame, with dampers being respectively coupled to the first and second portions of the body frame.